Hello / Salam

Welcome to my personal blog, here you can find info about Abolfazl (Abe) Arab!

Curriculum Vitae (CV)

I finished my high school in the city of Shiraz, studied undergraduate and a master in Tehran, and performed several years of research in the United States. Here are my education and work experiences. Education Research / Work Publications Presentations Experiences Education .tableContainer { margin-left: .75pt; border-collapse: collapse; border-spacing: 0; border: none; } .cell { vertical-align: top; width: 6.9in; border: none; padding: 0in 5.4pt 0in 5.4pt; height: 15....

January 25, 2024 · Abe

RNA Dynamics and Cellular Sensitivity to DNA Hypomethylation – Systems Biology Approach

Understanding the intricacies of DNA methylation is essential for unraveling the complexities of epigenetic regulation in various biological processes, including cancer development and treatment. In the subsequent sections, we delve into the impact of decitabine, a DNA demethylating agent, on global DNA methylation patterns and RNA dynamics upon drug treatment in the context of acute myeloid leukemia (AML) cancer treatment. Background Decitabine, a DNA demethylating agent, is a drug with an epigenetic therapy mechanism of action and an FDA approved strategy to treat high-risk patients with AML cancer....

December 17, 2023 · Abe